Ten-year longitudinal change in aortic stiffness assessed by cardiac MRI in the second half of the human lifespan: the multi-ethnic study of atherosclerosis
Aims: To examine the determinants of change in thoracic aortic stiffness with a 10-year follow-up on the MESA population, measured by MRI.
The maximum and minimum cross-sectional areas of the ascending and descending aorta were measured with automated software ARTFUN. Aortic strain and distensibility were then calculated with these measures.
Age, mean blood pressure and smoking, were related to a reduction in AAD and DAD and an increase in PWV throughout the follow-up period.
Increase in blood pressure during the 10-year follow-up period were associated with progressive aortic stiffness.
Blood pressure control is effective in halting the progression of aortic stiffening. Main factors of aortic stiffness, are age, blood pressure, and smoking.
Authors : Yoshiaki Ohyama,Gisela Teixido-Tura,Bharath Ambale-Venkatesh,Chikara Noda, Atul R. Chugh, Chia-Ying Liu, Alban Redheuil,R. Brandon Stacey, Harry Dietz, Antoinette S. Gomes, Martin R. Prince,Arturo Evangelista, Colin O. Wu,W. Gregory Hundley, David A. Bluemke, and Joao A.C. Lima
Clinical Application : Atherosclerosis / Vascular aging
Country : USA
Date Publication : 2016
Nbre citation : 29